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= Welcome to FDR Genetics Mutations Period 3 Ms Ruebe's Class! = This wiki is designed for students to gather and share information about genetic mutations.

Objective

 * **Define** and **explain** the genetic disease/syndrome you have been assigned.
 * **Explain** how your genetic disease occurs- gene or chromosomal mutation.
 * **Explain** the **benefits** **and limitations** of your genetic disease, these may include the identification process or how gene therapy and genetic engineering is being used.
 * **Discuss** how social, economical, cultural and ethical issues are associated with your disease/syndrome.
 * Make sure to **communicate** using scientific information **effectively** and **correctly**.
 * **Present** the information in multiple forms. Remember to include visual representations (IE. diagrams, images of karyotypes, pictures of individuals, DNA sequences, etc.)
 * Acknowledge the sources of information you have accessed by attaching a bibliography as a separate sheet, using proper MLA citation.

**How to use it**: At the bar at the left you can find different pages. Begin by going to All Tasks to start your assignment. Each page leads you to a different content. For example, in Cloning you will find a things about that topic. Be free to explore the different pages that we are elaborating. **Note**: All your changes will be saved in History. People will be able to see what you did.That way, the teacher can give you credit for your collaboration or participation.
 * Warning!!**: Your changes will not be saved if you do not put **SAVE** at the top. Never close without saving. If you close without saving your whole writing or changes you made will not be displayed for people to see.

**Criterion A Score: ___ Criterion B Score:__ _ ** || || **MYP Rubrics: Science ** =**Footnote citations**= =For each non original idea - something you learned from a website- must be cited.= For example: "Footnotes and Endnotes are used to give credit to sources of any material borrowed, summarized or paraphrased" [|1].
 * Your work will be assessed for MYP Science Criteria A (One World) and B (Communication). **
 * || **MYP Rubrics: Science ** ||
 * **Achievement Level ** || **Criterion A: One World ** || **Achievement Level ** || **Criterion B: Communication in science ** ||
 * **0 ** || The student does not reach a standard described by any of the descriptors below. || **0 ** || The student does not reach a standard described by any of the descriptors below. ||
 * **1 – 2 ** || The student **describes** how their genetic disease/syndrome occurred. The student **states two** of the benefits **or** limitations of their genetic disease/syndrome. || **<span style="font-family: 'Times New Roman','serif'; font-size: 10px;">1 – 2 ** || <span style="font-family: 'Times New Roman','serif'; font-size: 10px;">The student **attempts** to communicate scientific information using **some scientific language specific to their genetic disease/syndrome**. The student presents some of the information in an appropriate form using some visual representation when appropriate. The student uses correct citation of 1 source. The student attempts to acknowledge sources of information but this is **inaccurate**. ||
 * **<span style="font-family: 'Times New Roman','serif'; font-size: 10px;">3 – 4 ** || <span style="font-family: 'Times New Roman','serif'; font-size: 10px;">The student **describes** how their genetic disease/syndrome occurred. The student **describes two** of the benefits **and one** limitation of their genetic disease/syndrome. The student **describes** how their genetic disease/syndrome is affected by at least **one** of the following factors: social, economic, cultural and ethical. || **<span style="font-family: 'Times New Roman','serif'; font-size: 10px;">3 – 4 ** || <span style="font-family: 'Times New Roman','serif'; font-size: 10px;">The student communicates scientific information using **scientific language specific to their genetic disease/syndrome**. The student presents most of the information appropriately using visual representation according to the task. The student uses correct citation of **3 sources**. The student acknowledges sources of information **with no more than one error or omission in the MLA citations**. ||
 * **<span style="font-family: 'Times New Roman','serif'; font-size: 10px;">5 – 6 ** || <span style="font-family: 'Times New Roman','serif'; font-size: 10px;">The student **explains** how their genetic disease/syndrome occurred. The student **explains two** of the benefits **and two** of the limitations of their genetic disease/syndrome. The student **discusses** how their genetic disease/syndrome is affected by at least **two** of the following factors: social, economic, cultural and ethical. || **<span style="font-family: 'Times New Roman','serif'; font-size: 10px;">5 – 6 ** || <span style="font-family: 'Times New Roman','serif'; font-size: 10px;">The student communicates scientific information **effectively** using **scientific language correctly specific to their genetic disease/syndrome**. The student presents all the information appropriately using visual representation accurately according to the task. The student uses correct citation of **5 sources**. The student acknowledges sources of information **appropriately with no errors using MLA citations**. ||

At the bottom of your information: =References= 1. [|A Research Guide for Students] 2010-11-12

<span style="font-family: 'Times New Roman','serif'; font-size: 16px;">Down Syndrome is a Chromosome mutation which was caused from an extra 21 chromosome being distributed into one of the gametes of the parents during meiosis.
 * <span style="font-family: 'Times New Roman','serif'; font-size: 16px;">Example: **
 * <span style="font-family: 'Times New Roman','serif'; font-size: 16px;">Describes = Gives a detailed account. **
 * <span style="font-family: 'Times New Roman','serif'; font-size: 16px;">Example: **<span style="font-family: 'Times New Roman','serif'; font-size: 16px;"> Describe how the genetic disease/syndrome occurred:

<span style="font-family: 'Times New Roman','serif'; font-size: 16px;">Down Syndrome is a Chromosome mutation which was caused from an unequal distribution of chromosomes in the meiotic division of gametes. This is where the spindle fibers do not attach to the centromere (middle section of the chromosome) during metaphase I or II. Therefore an extra 21 chromosome is distributed into one of the gametes of the parents.
 * <span style="font-family: 'Times New Roman','serif'; font-size: 16px;">Explain = Gives a detailed account of causes, reasons or mechanisms. **
 * <span style="font-family: 'Times New Roman','serif'; font-size: 16px;">Example **<span style="font-family: 'Times New Roman','serif'; font-size: 16px;">: Explain how genetic disease/syndrome occurred:

<span style="font-family: 'Times New Roman','serif'; font-size: 16px;">Down Syndrome is a Chromosome mutation which was caused from an unequal distribution of chromosomes in the meiotic division of gametes. This is where the spindle fibers do not attach to the centromere (middle section of the chromosome) during prophase I or II and therefore creating unequal distribution of the chromosomes. An extra 21 chromosome is distributed into one of the gametes of the parents. When the egg is fertilized with the sperm, the fertilized zygote (egg) has 47 chromosome (47 XX or XY+21) instead of the normal 46 XX or XY. <span style="font-family: 'Times New Roman','serif'; font-size: 16px;">The incidence of Down syndrome (Trisomy 21) rises sharply with increasing maternal age. After the age of 40 years in a female the risk of conceiving a child with Down syndrome is 1 in 100 and those over the age of 45 years have a 1 in 30 chance (Medicine Net, 2010).
 * <span style="font-family: 'Times New Roman','serif'; font-size: 16px;">Discusses = Give an account including, where possible, a range of arguments for and against the relative importance of various factors, or comparisons of alternative hypotheses. **
 * <span style="font-family: 'Times New Roman','serif'; font-size: 16px;">Example: **<span style="font-family: 'Times New Roman','serif'; font-size: 16px;"> Discuss how genetic disease/syndrome occurred:

= = = **Crohn's desease** = = =

=
This disorder causes the inmune system to attack healthy tissues and harm them. the tissues involved in this disease are the small intestine, the large intestine, the rectum or the mouth, and depending of the affected area it is determined in one of the different types. =====